(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid

Product Name: (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid
CAS No.: 1072833-77-2
Chemical Name: (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid
Synonyms: IxazoMib;MLN2238;Ixazomib-d7;CS-1976;MLN2238(Ixazomib);MLN2238(iaxzomib);ixazomib(MLN2238);Ixazomib (MLN-9708);Ixazomib (10mM in DMSO);MLN2238;MLN 2238;MLN-2238
CBNumber: CB62521080
Molecular Formula: C14H19BCl2N2O4
Formula Weight: 361.03
MOL File: 1072833-77-2.mol

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(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid Property

Melting point:: >142°C (subl.)
Density: 1.306
storage temp.: -20°C Freezer
solubility: DMSO (Sparingly), Methanol (Slightly)
pka: 9.67±0.43(Predicted)
form: Solid
color: White to Pale Yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H360May damage fertility or the unborn child

H362May cause harm to breast-fed children

Precautionary statements

P201Obtain special instructions before use.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P263Avoid contact during pregnancy/while nursing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 18385
Product name: MLN2238
Purity: ≥95%
Packaging: 1mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 18385
Product name: MLN2238
Purity: ≥95%
Packaging: 5mg
Price: $193
Updated: 2024/03/01

Cayman Chemical

Product number: 18385
Product name: MLN2238
Purity: ≥95%
Packaging: 10mg
Price: $341
Updated: 2024/03/01

Cayman Chemical

Product number: 18385
Product name: MLN2238
Purity: ≥95%
Packaging: 50mg
Price: $1169
Updated: 2024/03/01

TRC

Product number: I942000
Product name: Ixazomib
Packaging: 100mg
Price: $700
Updated: 2021/12/16

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(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid Chemical Properties,Usage,Production

Uses

Ixazomib is a proteasome inhibitor that acts by preventing cell growth in solid tumours. It is an anticancer agent that is used to treat patients with multiple myeloma and is potentially neurotoxic.

Definition

ChEBI: A glycine derivative that is the amide obtained by formal condensation of the carboxy group of N-(2,5-dichlorobenzoyl)glycine with the amino group of [(1R)-1-amino-3-methylbutyl]boronic acid. The active metabolite of ixa omib citrate, it is used in combination therapy for treatment of multiple myeloma.

target

chymotrypsin-like proteolytic (β5) site of the 20S proteasome

(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid Suppliers

China 166 China Hong Kong 1 India 5 United Kingdom 1 United States 23 Global 196

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View Lastest Price from (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid manufacturers

Henan Fengda Chemical Co., Ltd

Product: (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid 1072833-77-2
Price: US $6.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-03-28

WUHAN FORTUNA CHEMICAL CO., LTD

Product: (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid 1072833-77-2
Price: US $0.00/g
Min. Order: 1g
Purity: 98%-102%
Supply Ability: 100G
Release date: 2021-06-29

Career Henan Chemical Co

Product: (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid 1072833-77-2
Price: US $2.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2018-12-24

1072833-77-2, (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acidRelated Search:

Ixazomib citrate (USAN) Acetamide, 2-amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]- Ixazomib Impurity 1 CUDC-101 Brivanib alaninate AC480 (BMS-599626) 1H-indazole-7-carboxylic acid tert-butyl (S)-3-(4-bromophenyl)piperidine-1-carboxylate Niraparib (S)-tert-butyl 3-(4-aMinophenyl)piperidine-1-carboxylate Piperidine, 3-(4-bromophenyl)- (aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate 4-piperidin-3-ylaniline CHEMBRDG-BB 7959525 Methyl 3-formyl-2-nitrobenzoate Bortezomib MLN9708 MK-2206 2HCl

MLN2238

IxazoMib

(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid

IXAZOMIB;MLN 2238;MLN-2238

CS-1976

1-(2-(2,5-dichlorobenzamido)acetamido)- 3-methylbutylboronic acid

B-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid

ixazomib(MLN2238)

B-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid Ixazomib (MLN2238)

MLN2238(iaxzomib)

MLN2238(Ixazomib)

MLN2238;MLN 2238;MLN-2238

Ixazomib (MLN-9708)

Ixazomib-d7

Ixazomib, 98%, a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM)

(1R)-1-{2-[(2,5-dichlorophenyl)formamido]acetamido}-3-methylbutyl]boronic acid

Boronic acid, B-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]-

(R)-(1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbuyl)boronic acid

Ixazomib (10mM in DMSO)

Ixazomib-13C2,15NQ: What is Ixazomib-13C2,15N Q: What is the CAS Number of Ixazomib-13C2,15N

1072833-77-2

C14H19BCl2N2O4

Inhibitors

Inhibitor

apis